PDZK1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728618

Détail du produit

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PDZK1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PDZD1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: Pdzd1 (PDZK1 Produits)

Synonymes: xpdzk1 Protein, PDZK1 Protein, CAP70 Protein, CLAMP Protein, NHERF-3 Protein, NHERF3 Protein, PDZD1 Protein, 1700023D20Rik Protein, 2610507N21Rik Protein, 4921513F16Rik Protein, AI267131 Protein, AI314638 Protein, AL022680 Protein, D3Ertd537e Protein, Pdzd1 Protein, mPDZK1 Protein, Clamp Protein, PDZ domain containing 1 Protein, PDZ domain containing 1 L homeolog Protein, PDZK1 Protein, pdzk1.L Protein, pdzk1 Protein, Pdzk1 Protein

Sujet: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 56.9 kDa

NCBI Accession: NP_002605