PRDM12 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2729559

Détail du produit

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PRDM12 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PRDM12 / PFM9 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Autre désignation: Prdm12,pfm9 (PRDM12 Produits)

Synonymes: PRDM12 Protein, prdm12 Protein, MGC146714 Protein, PFM9 Protein, pfm9 Protein, Gm998 Protein, PR/SET domain 12 Protein, PR domain containing 12 Protein, PR domain containing 12 L homeolog Protein, PR domain containing 12a Protein, PRDM12 Protein, prdm12 Protein, prdm12.L Protein, Prdm12 Protein, prdm12a Protein

Sujet: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN&aposs) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.

Poids moléculaire: 40.2 kDa

NCBI Accession: NP_067632