PBX1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2729562

Détail du produit

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PBX1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Pre-B-cell leukemia homeobox 1 (PBX1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Autre désignation: Pre-B-Cell Leukemia Homeobox 1 (Pbx1) (PBX1 Produits)

Synonymes: fi29e01 Protein, pbx1b Protein, wu:fi29e01 Protein, zgc:55265 Protein, 2310056B04Rik Protein, AI848790 Protein, AU015730 Protein, D230003C07Rik Protein, Pbx-1 Protein, Pbx1a Protein, Pbx1b Protein, PBX1A Protein, Xpbx1 Protein, Xpbx1b Protein, PBX homeobox 1 Protein, pre-B-cell leukemia homeobox 1a Protein, pre B cell leukemia homeobox 1 Protein, pre-B-cell leukemia homeobox 1 S homeolog Protein, PBX1 Protein, pbx1a Protein, Pbx1 Protein, pbx1.S Protein

Sujet: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(119) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 46.4 kDa

NCBI Accession: NP_002576