PTPN18 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730112

Détail du produit

Antigène: PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PTPN18 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PTPN18 / BDP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))

Autre désignation: Ptpn18,bdp1 (PTPN18 Produits)

Synonymes: BDP1 Protein, PTP-HSCF Protein, FLP1 Protein, HSCF Protein, PTP-K1 Protein, Ptpk1 Protein, PTP20 Protein, protein tyrosine phosphatase, non-receptor type 18 Protein, PTPN18 Protein, Ptpn18 Protein

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 50.3 kDa

NCBI Accession: NP_055184