PUF60 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730160

Détail du produit

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PUF60 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PUF60 / SIAHBP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Fiorentino, Presby, Baer, Petri, Rieger, Soloski, Rosen, Mammen, Christopher-Stine, Casciola-Rosen: "PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome." dans: Annals of the rheumatic diseases, Vol. 75, Issue 6, pp. 1145-51, (2016) (PubMed).

Détail du antigène

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Autre désignation: Puf60,siahbp1 (PUF60 Produits)

Synonymes: FIR Protein, RoBPI Protein, SIAHBP1 Protein, fc21a05 Protein, wu:fc21a05 Protein, wu:fi43a08 Protein, 2410104I19Rik Protein, 2810454F19Rik Protein, Siahbp1 Protein, fe37c05 Protein, repressor Protein, si:ch211-12p8.2 Protein, si:zc12p8.2 Protein, wu:fb33e11 Protein, wu:fe37c05 Protein, zgc:86806 Protein, poly(U) binding splicing factor 60 Protein, poly-U binding splicing factor a Protein, poly-U binding splicing factor 60 Protein, poly-U binding splicing factor b Protein, PUF60 Protein, puf60a Protein, Puf60 Protein, puf60b Protein

Sujet: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 59.7 kDa

NCBI Accession: NP_510965