RAB13 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730274

Détail du produit

Antigène: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RAB13 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RAB13 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Autre désignation: Rab13 (RAB13 Produits)

Synonymes: cb764 Protein, hm:zeh0455 Protein, RAB13 Protein, 0610007N03Rik Protein, B230212B15Rik Protein, RAB13, member RAS oncogene family Protein, rab13 Protein, RAB13 Protein, Rab13 Protein

Sujet: This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

Poids moléculaire: 22.6 kDa

NCBI Accession: NP_002861

Pathways: Cell-Cell Junction Organization