RAD18 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes RAD18 Protéines
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RAD18 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human RAD18 / RNF73 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD18 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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USP7 is essential for maintaining Rad18 stability and DNA damage tolerance." dans: Oncogene, Vol. 35, Issue 8, pp. 965-76, (2016) (PubMed).
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USP7 is essential for maintaining Rad18 stability and DNA damage tolerance." dans: Oncogene, Vol. 35, Issue 8, pp. 965-76, (2016) (PubMed).
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- Antigène
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Autre désignation
- Rad18,rnf73 (RAD18 Produits)
- Synonymes
- RNF73 Protein, 2810024C04Rik Protein, Rad18sc Protein, zgc:55577 Protein, RAD18 Protein, DDBDRAFT_0218120 Protein, DDBDRAFT_0304878 Protein, DDB_0218120 Protein, DDB_0304878 Protein, DKFZp469H0810 Protein, RAD18, E3 ubiquitin protein ligase Protein, RAD18 E3 ubiquitin protein ligase Protein, E3 ubiquitin-protein ligase RAD18 Protein, E3 ubiquitin-protein ligase Protein, DNA repair protein and ATPase Protein, C3HC4-type zinc finger-containing protein Protein, RAD18 Protein, Rad18 Protein, rad18 Protein
- Sujet
- The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
- Poids moléculaire
- 56 kDa
- NCBI Accession
- NP_064550
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