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Rhotekin Protein (RTKN) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

RTKN Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2730883
  • Antigène Voir toutes Rhotekin (RTKN) Protéines
    Rhotekin (RTKN)
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    • 5
    • 2
    • 2
    Humain
    Source
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Rhotekin protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Rhotekin / RTKN (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RTKN Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    Rhotekin (RTKN)
    Autre désignation
    Rhotekin,rtkn (RTKN Produits)
    Synonymes
    RTKN Protein, rhotekin Protein, RTKN Protein, rtkn Protein, Rtkn Protein
    Sujet
    This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Poids moléculaire
    61 kDa
    NCBI Accession
    NP_149035
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