RING1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730932

Détail du produit

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RING1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RING1 / RNF1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Autre désignation: Ring1,rnf1 (RING1 Produits)

Synonymes: RING1A Protein, RNF1 Protein, Ring1A Protein, bap-1 Protein, bap1 Protein, ding Protein, hipi3 Protein, ring1a Protein, ring1b Protein, ring2 Protein, rnf1 Protein, rnf2-a Protein, ring1 Protein, ring1b-B Protein, rnf2-b Protein, ring finger protein 1 Protein, ring finger protein 1 S homeolog Protein, ring finger protein 1 L homeolog Protein, RING1 Protein, Ring1 Protein, ring1.S Protein, ring1.L Protein

Sujet: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Poids moléculaire: 42.2 kDa

NCBI Accession: NP_002922