SFTPB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2731916

Détail du produit

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SFTPB protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SFTPB (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Autre désignation: Sftpb (SFTPB Produits)

Synonymes: PSP-B Protein, SFTB3 Protein, SFTP3 Protein, SMDP1 Protein, SP-B Protein, AI562151 Protein, SF-B Protein, Sftp-3 Protein, Sftp3 Protein, Sp-b Protein, SFTPB Protein, sftpb Protein, xSP-B Protein, surfactant protein B Protein, surfactant associated protein B Protein, surfactant, pulmonary-associated protein B L homeolog Protein, SFTPB Protein, Sftpb Protein, sftpb.L Protein

Sujet: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010].

Poids moléculaire: 39.5 kDa

NCBI Accession: NP_942140