SH3BP1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2731971

Détail du produit

Antigène: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SH3BP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SH3BP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Autre désignation: Sh3bp1 (SH3BP1 Produits)

Synonymes: ARHGAP43 Protein, 3BP-1 Protein, SH3BP1 Protein, SH3 domain binding protein 1 Protein, SH3-domain binding protein 1 Protein, SH3 domain-binding protein 1 Protein, SH3BP1 Protein, Sh3bp1 Protein, LOC100398528 Protein

Sujet: This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein&aposs association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.

Poids moléculaire: 75.5 kDa

NCBI Accession: NP_061830