ORCTL-2/SLC22A18 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732154

Détail du produit

Antigène: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ORCTL-2/SLC22A18 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SLC22A18 / ORCTL2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Autre désignation: Slc22a18,orctl2 (SLC22A18 Produits)

Synonymes: MGC123168 Protein, zgc:123168 Protein, BWR1A Protein, BWSCR1A Protein, HET Protein, IMPT1 Protein, ITM Protein, ORCTL2 Protein, SLC22A1L Protein, TSSC5 Protein, p45-BWR1A Protein, AW260131 Protein, Impt1 Protein, Orctl2 Protein, Slc22a1l Protein, solute carrier family 22, member 18 Protein, solute carrier family 22 member 18 Protein, solute carrier family 22 (organic cation transporter), member 18 Protein, slc22a18 Protein, SLC22A18 Protein, Slc22a18 Protein

Sujet: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms&apos tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 44.7 kDa

NCBI Accession: NP_899056