SMOX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732257

Détail du produit

Antigène: SMOX (Spermine Oxidase (SMOX))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SMOX protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SMOX (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SMOX (Spermine Oxidase (SMOX))

Autre désignation: Smox (SMOX Produits)

Synonymes: cb1027 Protein, wu:fq32f10 Protein, zgc:77167 Protein, MGC81392 Protein, APAO Protein, ATPAO1 Protein, MSH12.17 Protein, MSH12_17 Protein, polyamine oxidase 1 Protein, C20orf16 Protein, PAO Protein, PAO-1 Protein, PAOH1 Protein, SMO Protein, B130066H01Rik Protein, PAOh1 Protein, spermine oxidase Protein, spermine oxidase S homeolog Protein, polyamine oxidase 1 Protein, smox Protein, SMOX Protein, smox.S Protein, PAO1 Protein, Smox Protein

Sujet: Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

Poids moléculaire: 55.9 kDa

NCBI Accession: NP_787034