Sorbs2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732362

Détail du produit

Antigène: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Sorbs2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Abstract: Sorbs2 Produits

Synonymes: Argbp2 Protein, 2010203O03Rik Protein, 9430041O17Rik Protein, A530071H08 Protein, mKIAA0777 Protein, argbp2 Protein, pro0618 Protein, 9430041O17RIK Protein, DKFZp468F1119 Protein, ARGBP2 Protein, PRO0618 Protein, sorbin and SH3 domain containing 2 Protein, Sorbs2 Protein, SORBS2 Protein, sorbs2 Protein

Sujet: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 69.8 kDa

NCBI Accession: NP_003594