SF3B2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732607

Détail du produit

Antigène: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SF3B2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Splicing factor 3b, subunit 2, 145 kDa (SF3B2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Abstract: SF3B2 Produits

Synonymes: 145kDa Protein, 2610311M13Rik Protein, 2810441F20Rik Protein, B230398H18Rik Protein, SAP145 Protein, SF3b1 Protein, SF3b145 Protein, SF3b150 Protein, SF3B2 Protein, cus1 Protein, sap145 Protein, sf3b145 Protein, sf3b150 Protein, Cus1 Protein, SF3B145 Protein, splicing factor 3b, subunit 2 Protein, splicing factor 3b subunit 2 Protein, splicing factor 3B subunit 2 Protein, splicing factor 3b subunit 2 L homeolog Protein, Sf3b2 Protein, SF3B2 Protein, LOC714747 Protein, sf3b2.L Protein, sf3b2 Protein

Sujet: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Poids moléculaire: 100 kDa

NCBI Accession: NP_006833