NCOA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732659

Détail du produit

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NCOA1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SRC1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Autre désignation: Src1 (NCOA1 Produits)

Synonymes: F-SRC-1 Protein, KAT13A Protein, RIP160 Protein, SRC1 Protein, bHLHe42 Protein, bHLHe74 Protein, si:dkey-5g7.6 Protein, si:dkey-34f16.6 Protein, NCOA1 Protein, SRC-1 Protein, nuclear receptor coactivator 1 Protein, NCOA1 Protein, ncoa1 Protein, Ncoa1 Protein

Sujet: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 59.7 kDa

NCBI Accession: NP_005408

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha