SSX2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732727

Détail du produit

Antigène: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SSX2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SSX2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Autre désignation: Ssx2 (SSX2 Produits)

Synonymes: CT5.2 Protein, CT5.2A Protein, HD21 Protein, HOM-MEL-40 Protein, SSX Protein, SSX2 Protein, SSX3 Protein, SSX family member 2 Protein, protein SSX2 Protein, synovial sarcoma, X breakpoint 2 Protein, SSX2 Protein, LOC741661 Protein, Ssx2 Protein

Sujet: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X18)(p11.2q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Poids moléculaire: 21.4 kDa

NCBI Accession: NP_783629