TGIF1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2733528

Détail du produit

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TGIF1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TGIF1 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Autre désignation: Tgif1 (TGIF1 Produits)

Synonymes: HPE4 Protein, TGIF Protein, AA959811 Protein, AI462167 Protein, Tgif Protein, Tfig Protein, fa06h05 Protein, fb33g11 Protein, zgc:55852 Protein, wu:fa06h05 Protein, wu:fb33g11 Protein, hpe4 Protein, tgif Protein, tgif1 Protein, TGFB induced factor homeobox 1 Protein, TGFB-induced factor homeobox 1 Protein, TGFB induced factor homeobox 1 S homeolog Protein, TGIF1 Protein, Tgif1 Protein, tgif1 Protein, tgif1.S Protein

Sujet: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.

Poids moléculaire: 29.6 kDa

NCBI Accession: NP_775300

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation