THRB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2733597

Détail du produit

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette THRB protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human THRB / ERBA2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Autre désignation: Thrb,erba2 (THRB Produits)

Synonymes: C-ERBA-2 Protein, C-ERBA-BETA Protein, ERBA2 Protein, GRTH Protein, NR1A2 Protein, PRTH Protein, THR1 Protein, THRB1 Protein, THRB2 Protein, Nr1a2 Protein, T3R[b] Protein, T3Rbeta Protein, Thrb1 Protein, Thrb2 Protein, c-erbAbeta Protein, TR-beta Protein, TR[b]1 Protein, fj24f03 Protein, trb Protein, wu:fj24f03 Protein, CTR BETA 2 Protein, TR-BETA Protein, LOC734147 Protein, thrb Protein, THRB Protein, C-erba-beta Protein, RATT3REC Protein, T3rec Protein, TRbeta Protein, THR Protein, TRbeta1 Protein, thyroid hormone receptor beta Protein, thyroid hormone receptor, beta Protein, thyroid hormone receptor, beta S homeolog Protein, thyroid hormone receptor, beta L homeolog Protein, THRB Protein, Thrb Protein, thrb Protein, thrb.S Protein, thrb.L Protein

Sujet: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Poids moléculaire: 52.6 kDa

NCBI Accession: NP_001121648

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound