TRIB2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2734213

Détail du produit

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TRIB2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TRIB2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Autre désignation: Trib2 (TRIB2 Produits)

Synonymes: TRIB2 Protein, Trb2 Protein, Xtrbl Protein, gs3955 Protein, c5fw Protein, trb2 Protein, xtrb2 Protein, TRB2 Protein, C5FW Protein, GS3955 Protein, TRB-2 Protein, AW319517 Protein, RGD1564451 Protein, tribbles pseudokinase 2 Protein, tribbles pseudokinase 2 S homeolog Protein, TRIB2 Protein, trib2 Protein, trib2.S Protein, Trib2 Protein

Sujet: This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 38.6 kDa

NCBI Accession: NP_067675