Tumor Protein p73 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

N° du produit ABIN2734637

Détail du produit

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 4

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Tumor Protein p73 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Tumor protein p73 (TP73) (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Abstract: TP73 Produits

Synonymes: P73 Protein, Trp73 Protein, TP73 Protein, tp73 Protein, Tp73 Protein, p73 Protein, TAp73 Protein, zp73theta Protein, tumor protein p73 Protein, transformation related protein 73 Protein, TP73 Protein, Tp73 Protein, tp73 Protein, Trp73 Protein

Sujet: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Poids moléculaire: 47.5 kDa

NCBI Accession: NP_001119714

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus