SNRPA1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2734735

Détail du produit

Antigène: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SNRPA1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human U1 snRNP protein A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Biological Activity Comment: : OriGene human recombinant small nuclear ribonucleoprotein polypeptide A (SNRPA) was compared side-by-side with baculovirus based insect cell (BEVS) derived SNRPA in a phycoerythrin detecting Luminex assay. The human cell produced SNRPA is comparative or better in sensitivity than the insect cell produced SNRPA to detect autoantibodies in human serum samples.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: > 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Autre désignation: u1 Snrnp Protein A (SNRPA Produits)

Synonymes: Mud1 Protein, U1-A Protein, U1A Protein, im:7142962 Protein, zgc:101832 Protein, C430021M15Rik Protein, Rnu1a-1 Protein, Rnu1a1 Protein, mud1 Protein, snf Protein, fc19d01 Protein, wu:fc19d01 Protein, zgc:77810 Protein, T30B22.12 Protein, U1SNRNP-SPECIFIC PROTEIN Protein, spliceosomal protein U1A Protein, small nuclear ribonucleoprotein polypeptide A Protein, small nuclear ribonucleoprotein polypeptide A' Protein, small nuclear ribonucleoprotein polypeptide A S homeolog Protein, spliceosomal protein U1A Protein, SNRPA Protein, snrpa1 Protein, Snrpa Protein, snrpa.S Protein, snrpa Protein, U1A Protein

Sujet: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5&apos splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Poids moléculaire: 31.1 kDa

NCBI Accession: NP_004587