UBE2D2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2734797

Détail du produit

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette UBE2D2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human UBE2D2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Autre désignation: Ube2d2 (UBE2D2 Produits)

Synonymes: E2(17)KB2 Protein, PUBC1 Protein, UBC4 Protein, UBC4/5 Protein, UBCH5B Protein, 1500034D03Rik Protein, Ubc2e Protein, Ube2d2 Protein, ubc4 Protein, ube2d2 Protein, zgc:55886 Protein, E217kB Protein, ubiquitin conjugating enzyme E2 D2 Protein, ubiquitin-conjugating enzyme E2D 2A Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2D 2 Protein, ubiquitin conjugating enzyme E2 D3 Protein, UBE2D2 Protein, Ube2d2a Protein, ube2d2 Protein, Ube2d2 Protein, UBE2D3 Protein

Sujet: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.

Poids moléculaire: 16.6 kDa

NCBI Accession: NP_003330

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades