UGT2B15 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2734994

Détail du produit

Antigène: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette UGT2B15 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human UGT2B15 / UGT2B8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Divakaran, Hines, McCarver: "Human hepatic UGT2B15 developmental expression." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 141, Issue 1, pp. 292-9, (2014) (PubMed).

Détail du antigène

Antigène: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Autre désignation: Ugt2b15,ugt2b8 (UGT2B15 Produits)

Synonymes: UGT2B28 Protein, HLUG4 Protein, UDPGT 2B8 Protein, UDPGT2B15 Protein, UDPGTH3 Protein, UGT2B8 Protein, UDP-glucuronosyltransferase 2B15 Protein, UDP glucuronosyltransferase family 2 member B15 Protein, LOC461289 Protein, LOC100591991 Protein, UGT2B15 Protein

Sujet: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 60.9 kDa

NCBI Accession: NP_001067

Pathways: Steroid Hormone Biosynthesis