UNC13D Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2735014

Détail du produit

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette UNC13D protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human UNC13D protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Autre désignation: Unc13d (UNC13D Produits)

Synonymes: FHL3 Protein, HLH3 Protein, HPLH3 Protein, Munc13-4 Protein, UNC13D Protein, 2610108D09Rik Protein, Jinx Protein, mFLJ00067 Protein, Unc13h4 Protein, BIGH3 Protein, CDB1 Protein, CDG2 Protein, CDGG1 Protein, CSD Protein, CSD1 Protein, CSD2 Protein, CSD3 Protein, EBMD Protein, LCD1 Protein, unc-13 homolog D Protein, unc-13 homolog D (C. elegans) Protein, transforming growth factor beta induced Protein, UNC13D Protein, Unc13d Protein, TGFBI Protein, unc13d Protein, un13d Protein

Sujet: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Poids moléculaire: 123.1 kDa

NCBI Accession: NP_954712

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process