VPREB3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2735411

Détail du produit

Antigène: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette VPREB3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human VPREB3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Autre désignation: Vpreb3 (VPREB3 Produits)

Synonymes: 8HS-20 Protein, Vpreb-3 Protein, AI528709 Protein, VPREB3 Protein, 8HS20 Protein, N27C7-2 Protein, pre-B lymphocyte gene 3 Protein, V-set pre-B cell surrogate light chain 3 Protein, pre-B lymphocyte 3 Protein, Ig lambda-6 chain C region Protein, Vpreb3 Protein, VPREB3 Protein, LOC698694 Protein

Sujet: The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.

Poids moléculaire: 13.5 kDa

NCBI Accession: NP_037510

Pathways: Production of Molecular Mediator of Immune Response