ZYX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2736195

Détail du produit

Antigène: ZYX (Zyxin (ZYX))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ZYX protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Zyxin (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ZYX (Zyxin (ZYX))

Autre désignation: Zyxin (ZYX Produits)

Synonymes: BcDNA:LD06023 Protein, CG32018 Protein, DLim-1 Protein, DmLIM-1 Protein, Dmel\\CG32018 Protein, Lim102EF Protein, ZYX102 Protein, Zyx102 Protein, Zyx102EF Protein, lim Protein, zyx102 Protein, zyxin Protein, zgc:171680 Protein, ZYX Protein, zyx Protein, MGC145270 Protein, ESP-2 Protein, HED-2 Protein, 9530098H06Rik Protein, R75157 Protein, Zyxin Protein, zyxin Protein, zyxin S homeolog Protein, zyx-1 Protein, Zyx Protein, zyx Protein, ZYX Protein, EDI_201420 Protein, zyx.S Protein

Sujet: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Poids moléculaire: 61.1 kDa

NCBI Accession: NP_001010972