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CLEC7A Protein (AA 72-244) (Fc Tag)

CLEC7A Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS
N° du produit ABIN2745633
  • Antigène Voir toutes CLEC7A Protéines
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 72-244
    Origine
    • 7
    • 5
    • 1
    • 1
    Souris
    Source
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CLEC7A protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Souris
    Attributs du produit
    Mouse dectin-1 (aa 72-244) is fused at the C-terminus to the Fc portion of human IgG1.
    Pureté
    >95 % (SDS-PAGE)
    niveau d'endotoxine
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product CLEC7A Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Autre désignation
    Dectin-1 (CLEC7A Produits)
    Synonymes
    CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
    Sujet
    Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
    Poids moléculaire
    ~56kDa (SDS-PAGE)
    UniProt
    Q6QLQ4
    Pathways
    Activation of Innate immune Response
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