DLK1 Protein (AA 24-303, Extracellular Domain) (Fc Tag)

N° du produit ABIN2745649

Détail du produit

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: Extracellular Domain, AA 24-303

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DLK1 protéine est marqué à la Fc Tag.

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Signal peptide and extracellular domain of human DLK1 (aa 24-303) are fused at the C-terminus to the Fc portion of human IgG1.

Pureté: >90 % (SDS-PAGE)

niveau d'endotoxine: <0.01EU/μg purified protein (LAL test, Lonza).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Inhibits adipogenesis of 3T3L-1 cells.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile water.

Concentration: Lot specific

Buffer: Lyophilized. Contains PBS + 0.02 % CHAPS.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1 (DLK1 Produits)

Synonymes: DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, Zog Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 homolog (Drosophila) Protein, delta-like 1 (Drosophila) Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, Dlk1 Protein

Sujet: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Poids moléculaire: ~65kDa (SDS-PAGE)

UniProt: P80370