IL-1 beta Protéine
Aperçu rapide pour IL-1 beta Protéine (ABIN2830810)
Antigène
Voir toutes IL-1 beta (IL1B) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Séquence
- APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS
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Attributs du produit
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10.G4.1 cells is less than 10 pg/mL, corresponding to a specific activity of > 1.0 x 108 IU/mg.
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Stérilité
- 0.2 μm filtered
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- IL1B
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Sujet
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Relevance: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Synonyms: IL-1 beta, -
Poids moléculaire
- 17.3 kDa
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UniProt
- P48090
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène
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