TADA2L Protein (His tag)

N° du produit ABIN5505791

Détail du produit

Antigène: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TADA2L protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Purified recombinant protein of Human transcriptional adaptor 2A (TADA2A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Autre désignation: transcriptional adaptor 2A (TADA2A Produits)

Synonymes: MGC81519 Protein, TADA2A Protein, TADA2L Protein, ADA2 Protein, ADA2A Protein, hADA2 Protein, AV319371 Protein, D030022J10Rik Protein, Tada2l Protein, tada2l Protein, zgc:154057 Protein, transcriptional adaptor 2A L homeolog Protein, transcriptional adaptor 2A Protein, tada2a.L Protein, TADA2A Protein, Tada2a Protein, tada2a Protein

Sujet: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.

Poids moléculaire: 35.9 kDa

NCBI Accession: NP_597683

Pathways: Chromatin Binding