ANAPC15 Protein (AA 1-121, full length) (GST tag)

N° du produit ABIN5709159

Détail du produit

Antigène: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-121

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ANAPC15 protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS)

Séquence: MSTLFPSLFP RVTETLWFNL DRPCVEETEL QQQEQQHQAW LQSIAEKDNN LVPIGKPASE HYDDEEEEDD EDDEDSEEDS EDDEDMQDMD EMNDYNESPD DGEVNEVDME GNEQDQDQWM I

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Autre désignation: APC15 (ANAPC15 Produits)

Synonymes: APC15 Protein, C11orf51 Protein, C15H11orf51 Protein, anaphase promoting complex subunit 15 Protein, ANAPC15 Protein

Sujet: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assbly checkpoint. Also required for degradation of CDC20.

Poids moléculaire: 41.7 kDa

UniProt: P60006