HIST1H2BD Protein (AA 2-126) (His-SUMO Tag)

N° du produit ABIN5709659

Détail du produit

Antigène: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Type de proteíne: Recombinant

Attributs du protein: AA 2-126

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HIST1H2BD protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: PEPSKSAPAP KKGSKKAITK AQKKDGKKRK RSRKESYSIY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Autre désignation: H2B1B (HIST1H2BD Produits)

Synonymes: HIST1H2BI Protein, H2B.1B Protein, H2B/b Protein, H2BFB Protein, HIRIP2 Protein, dJ221C16.6 Protein, histone cluster 1, H2bd Protein, histone cluster 1 H2B family member d Protein, HIST1H2BD Protein

Sujet: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.

Poids moléculaire: 29.81 kDa

UniProt: P33778

Pathways: Telomere Maintenance