HMGCR Protein (AA 588-887, partial) (His tag)

N° du produit ABIN5709669

Détail du produit

Antigène: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Type de proteíne: Recombinant

Attributs du protein: partial, AA 588-887

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HMGCR protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MTRGPVVRLP RACDSAEVKA WLETSEGFAV IKEAFDSTSR FARLQKLHTS IAGRNLYIRF QSRSGDAMGM NMISKGTEKA LSKLHEYFPE MQILAVSGNY CTDKKPAAIN WIEGRGKSVV CEAVIPAKVV REVLKTTTEA MIEVNINKNL VGSAMAGSIG GYNAHAANIV TAIYIACGQD AAQNVGSSNC ITLMEASGPT NEDLYISCTM PSIEIGTVGG GTNLLPQQAC LQMLGVQGAC KDNPGENARQ LARIVCGTVM AGELSLMAAL AAGHLVKSHM IHNRSKINLQ DLQGACTKKT

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Autre désignation: HMDH (HMGCR Produits)

Synonymes: HMGR Protein, LDLCQ3 Protein, hmg-coa-r Protein, HMG-CoAR Protein, Red Protein, 3H3M Protein, BcDNA:LD15354 Protein, CG10367 Protein, Clb Protein, DmHMG-CoAr Protein, Dmel\\CG10367 Protein, HMGCR Protein, HMGCR_Dm Protein, HMGCoAR Protein, HMGCoARr Protein, HMGCoAr Protein, HmG-CoAR Protein, Hmg Protein, bro1 Protein, bs32f05.y1 Protein, clb Protein, hmgc Protein, hmgcr Protein, hmgrc Protein, l(3)01152 Protein, l(3)04684 Protein, hmgcr2 Protein, im:6912716 Protein, zgc:110746 Protein, 3-hydroxy-3-methylglutaryl-CoA reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Protein, HMG Coenzyme A reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase b Protein, HMGCR Protein, hmgcr.L Protein, Hmgcr Protein, hmgcrb Protein

Sujet: Transmbrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Poids moléculaire: 36.1 kDa

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha