KCNJ10 Protein (AA 165-379, Cytoplasmic Domain, Cytosolic) (His-SUMO Tag)

N° du produit ABIN5709795

Détail du produit

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Type de proteíne: Recombinant

Attributs du protein: Cytosolic, AA 165-379, Cytoplasmic Domain

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette KCNJ10 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: FLAKIARPKK RAETIRFSQH AVVASHNGKP CLMIRVANMR KSLLIGCQVT GKLLQTHQTK EGENIRLNQV NVTFQVDTAS DSPFLILPLT FYHVVDETSP LKDLPLRSGE GDFELVLILS GTVESTSATC QVRTSYLPEE ILWGYEFTPA ISLSASGKYI ADFSLFDQVV KVASPSGLRD STVRYGDPEK LKLEESLREQ AEKEGSALSV RISNV

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Autre désignation: KCJ10 (KCNJ10 Produits)

Synonymes: kir1.2 Protein, kir4.1 Protein, birk-10 Protein, MGC145926 Protein, BIR10 Protein, BIRK-1 Protein, Kir1.2 Protein, Kir4.1 Protein, BIRK-10 Protein, KCNJ13-PEN Protein, KIR1.2 Protein, KIR4.1 Protein, SESAME Protein, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog Protein, potassium voltage-gated channel subfamily J member 10 Protein, potassium channel, inwardly rectifying subfamily J, member 10 Protein, potassium inwardly-rectifying channel, subfamily J, member 10 Protein, kcnj10.L Protein, KCNJ10 Protein, kcnj10 Protein, Kcnj10 Protein

Sujet: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium .

Poids moléculaire: 39.8 kDa

UniProt: P78508

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity