KRT17 Protein (AA 1-441, full length) (His-SUMO Tag)
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- Antigène Voir toutes KRT17 Protéines
- KRT17 (Keratin 17 (KRT17))
- Type de proteíne
- Recombinant
- Attributs du protein
- full length, AA 1-441
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Origine
- Boeuf (Vache)
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette KRT17 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MTTTIRHFSS GSIKGSSGLA GGSSRSCRVS GSLGGGSCRL GSAGGLGSGL GGSSYSSCYS FGSGGGYGSG GYVSGGYGGG FGGVDGLLVG GEKATMQNLN DRLASYLDKV RALEEANTEL ELKIRDWYQK QAPGPAPDYS SYFKTIEDLR NKIHTATVDN ANLLLQIDNA RLAADDFRTK FETEQALRVS VEADINGLRR VLDELTLARA DLEMQIENLK EELAYLRKNH EEEMKALRGQ VGGEINVEMD AAPGVDLSRI LNEMRDQYEK MAEKNRKDAE DWFFSKTEEL NREVATNSEL VQSGKSEISE LRRTLQALEI ELQSQLSMKA SLEGSLAETE NRYCMQLSQI QGLIGSVEEQ LAQLRCEMEQ QNQEYKILLD VKTRLEQEIA TYRRLLEGED AHLTQYKTKE PVTTRQVRTI VEEVQDGRVI SSREQVHQTS H
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product KRT17 Protéine
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Keratin 17 (KRT17) (AA 1-432) protein (GST tag)
KRT17 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Keratin 17 (KRT17) (AA 1-432) protein (Strep Tag)Crystallography grade KRT17 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Keratin 17 (KRT17) (AA 1-433) protein (Strep Tag)Crystallography grade KRT17 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Keratin 17 (KRT17) (AA 1-432) protein (His tag)KRT17 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- KRT17 (Keratin 17 (KRT17))
- Autre désignation
- K1C17 (KRT17 Produits)
- Synonymes
- K17 Protein, Krt1-17 Protein, PC Protein, PC2 Protein, PCHC1 Protein, Ka17 Protein, KRT17 Protein, krt16 Protein, si:dkeyp-113d7.7 Protein, KRT14 Protein, keratin 17 Protein, keratin 17 L homeolog Protein, keratin 17, type I Protein, keratin, type I cytoskeletal 17 Protein, Krt17 Protein, KRT17 Protein, krt17 Protein, krt17.L Protein, LOC100737113 Protein, LOC102177275 Protein
- Sujet
- Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "st cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
- Poids moléculaire
- 64.71 kDa
- UniProt
- A1L595
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