MMP14 Protein (AA 112-582) (His-SUMO Tag)

N° du produit ABIN5709943

Détail du produit

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Type de proteíne: Recombinant

Attributs du protein: AA 112-582

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MMP14 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: YAIQGLKWQH NEITFCIQNY TPKVGEYATY EAIRKAFRVW ESATPLRFRE VPYAYIREGH EKQADIMIFF AEGFHGDSTP FDGEGGFLAH AYFPGPNIGG DTHFDSAEPW TVRNEDLNGN DIFLVAVHEL GHALGLEHSS DPSAIMAPFY QWMDTENFVL PDDDRRGIQQ LYGGESGFPT KMPPQPRTTS RPSVPDKPKN PTYGPNICDG NFDTVAMLRG EMFVFKERWF WRVRNNQVMD GYPMPIGQFW RGLPASINTA YERKDGKFVF FKGDKHWVFD EASLEPGYPK HIKELGRGLP TDKIDAALFW MPNGKTYFFR GNKYYRFNEE LRAVDSEYPK NIKVWEGIPE SPRGSFMGSD EVFTYFYKGN KYWKFNNQKL KVEPGYPKSA LRDWMGCPSG GRPDEGTEEE TEVIIIEVDE EGGGAVSAAA VVLPVLLLLL VLAVGLAVFF FRRHGTPRRL LYCQRSLLDK V

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14 (MMP14 Produits)

Synonymes: MMP1 Protein, MMP-14 Protein, MMP-X1 Protein, MT-MMP Protein, MT-MMP 1 Protein, MT1-MMP Protein, MT1MMP Protein, MTMMP1 Protein, mmp-x1 Protein, mt1-mmp Protein, mtmmp1 Protein, AI325305 Protein, MT-MMP-1 Protein, sabe Protein, Mt1-mmp Protein, MT-MMPbeta Protein, cb386 Protein, sb:cb386 Protein, wu:fb72b09 Protein, mmp14 Protein, matrix metallopeptidase 14 Protein, matrix metallopeptidase 14 (membrane-inserted) Protein, matrix metallopeptidase 14b (membrane-inserted) Protein, matrix metallopeptidase 14a (membrane-inserted) Protein, matrix metallopeptidase 14 L homeolog Protein, MMP14 Protein, mmp14 Protein, Mmp14 Protein, mmp14b Protein, mmp14a Protein, mmp14.L Protein

Sujet: Ses to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

Poids moléculaire: 69.8 kDa

UniProt: P50281

Pathways: Autophagy