NPHP1 Protein (AA 1-109, partial) (GST tag)
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- Antigène Voir toutes NPHP1 Protéines
- NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-109, partial
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette NPHP1 protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MLARRQRDPL QALRRRNQEL KQQVDSLLSE SQLKEALEPN KRQHIYQRCI QLKQAIDENK NALQKLSKAD ESAPVANYNQ RKEEEHTLLD KLTQQLQGLA VTISRENITE
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product NPHP1 Protéine
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Nephronophthisis 1 (Juvenile) (NPHP1) (AA 1-121) protein (GST tag)
NPHP1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Nephronophthisis 1 (Juvenile) (NPHP1) (AA 22-121) protein (GST tag)NPHP1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Nephronophthisis 1 (Juvenile) (NPHP1) (AA 1-732) protein (Strep Tag)Crystallography grade NPHP1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Nephronophthisis 1 (Juvenile) (NPHP1) (AA 1-687) protein (Strep Tag)Crystallography grade NPHP1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
- Autre désignation
- NPHP1 (NPHP1 Produits)
- Synonymes
- JBTS4 Protein, NPH1 Protein, SLSN1 Protein, nephrocystin-1 Protein, NPHP1 Protein, im:7162391 Protein, wu:fi59g07 Protein, zgc:152930 Protein, Nphp1 Protein, nephrocystin 1 Protein, nephronophthisis 1 (juvenile) homolog (human) Protein, nephronophthisis 1 (juvenile) L homeolog Protein, nephronophthisis 1 Protein, nephrocystin-1 Protein, NPHP1 Protein, Nphp1 Protein, nphp1.L Protein, nphp1 Protein, LOC100725987 Protein
- Sujet
- Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 . Does not se to be strictly required for ciliogenesis . Ses to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assbly. Required for normal retina development. In connecting photoreceptor cilia influences the movent of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis .
- Poids moléculaire
- 40.3 kDa
- UniProt
- O15259
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