PSIP1 Protein (AA 1-530, full length) (His-SUMO Tag)

N° du produit ABIN5710167

Détail du produit

Antigène: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-530

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PSIP1 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MTRDFKPGDL IFAKMKGYPH WPARVDEVPD GAVKPPTNKL PIFFFGTHET AFLGPKDIFP YSENKEKYGK PNKRKGFNEG LWEIDNNPKV KFSSQQAATK QSNASSDVEV EEKETSVSKE DTDHEEKASN EDVTKAVDIT TPKAARRGRK RKAEKQVETE EAGVVTTATA SVNLKVSPKR GRPAATEVKI PKPRGRPKMV KQPCPSESDI ITEEDKSKKK GQEEKQPKKQ PKKDEEGQKE EDKPRKEPDK KEGKKEVESK RKNLAKTGVT STSDSEEEGD DQEGEKKRKG GRNFQTAHRR NMLKGQHEKE AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK NSLKIDNLDV NRCIEALDEL ASLQVTMQQA QKHTEMITTL KKIRRFKVSQ VIMEKSTMLY NKFKNMFLVG EGDSVITQVL NKSLAEQRQH EEANKTKDQG KKGPNKKLEK EQTGSKTLNG GSDAQDGNQP QHNGESNEDS KDNHEASTKK KPSSEERETE ISLKDSTLDN

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Autre désignation: PSIP1 (PSIP1 Produits)

Synonymes: PSIP1 Protein, im:7149861 Protein, zgc:109898 Protein, LEDGF Protein, p75 Protein, PSIP2 Protein, DFS70 Protein, PAIP Protein, p52 Protein, AA408851 Protein, AU015605 Protein, Dfs70 Protein, Ledgfa Protein, Ledgfb Protein, Psip2 Protein, Ledgf Protein, SBP75 Protein, LEDGF/p75 Protein, PC4 and SFRS1 interacting protein 1 S homeolog Protein, PC4 and SFRS1 interacting protein 1 Protein, PC4 and SFRS1 interacting protein 1a Protein, LEDGF/p75 transcription factor-like Protein, psip1.S Protein, PSIP1 Protein, psip1a Protein, psip1 Protein, Psip1 Protein

Sujet: Transcriptional coactivator involved in neuroepithelial st cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Poids moléculaire: 76.1 kDa

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization