Reelin Protein (RELN) (AA 26-254, partial) (His tag)

N° du produit ABIN4976505

Détail du produit

Antigène: Reelin (RELN)

Type de proteíne: Recombinant

Attributs du protein: AA 26-254, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Reelin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: AAGYYPRFSP FFFLCTHHGE LEGDGEQGEV LISLHIAGNP TYYVPGQEYH VTISTSTFFD GLLVTGLYTS TSVQASQSIG GSSAFGFGIM SDHQFGNQFM CSVVASHVSH LPTTNLSFIW IAPPAGTGCV NFMATATHRG QVIFKDALAQ QLCEQGAPTD VTVHPHLAEI HSDSIILRDD FDSYHQLQLN PNIWVECNNC ETGEQCGAIM HGNAVTFCEP YGPRELITT

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: Reelin (RELN)

Autre désignation: RELN (RELN Produits)

Synonymes: LIS2 Protein, PRO1598 Protein, RL Protein, reeler Protein, rl Protein, Reelen Protein, Rl Protein, reln Protein, RELN Protein, MGC172539 Protein, reelin Protein, reelin L homeolog Protein, RELN Protein, Reln Protein, reln Protein, reln.L Protein, LOC579060 Protein

Sujet: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it ses to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation .

Poids moléculaire: 29 kDa

UniProt: P78509

Pathways: Synaptic Membrane