Bovine Coronavirus Spike Protein (AA 326-540, partial) (His tag)

N° du produit ABIN5710878

Détail du produit

Antigène: Bovine Coronavirus Spike (BCoV S) (Bovine Coronavirus Spike Protein (BCoV S))

Type de proteíne: Recombinant

Attributs du protein: AA 326-540, partial

Origine: Bovine Coronavirus (BCoV)

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Bovine Coronavirus Spike protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: PNLPDCNIEA WLNDKSVPSP LNWERKTFSN CNFNMSSLMS FIQADSFTCN NIEAAKIYGM CFSSITIDKF AIPNGRKVDL QLGNLGYLQS FNYRIDTTAA SCQLYYNLPA ANVSVSRFNP STWNRRFGFT EQSVFKPQPV GVFTHHDVVY AQHCFKAPTN FCPCKLDGSL CVGNGPGIDA GYKNSGIGTC PAGTNYLTCH NAAQCDCLCT PDPIT

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: Bovine Coronavirus Spike (BCoV S) (Bovine Coronavirus Spike Protein (BCoV S))

Autre désignation: Bovine Corona Virus Peplomer Protein (BCoV S Produits)

Classe de substances: Viral Protein

Sujet: S1 attaches the virion to the cell mbrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell mbrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell mbranes .

Poids moléculaire: 27.7 kDa

UniProt: P25194