NR1H3 Protein (AA 1-402, Isoform 3) (His-SUMO Tag)
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- Antigène Voir toutes NR1H3 Protéines
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Type de proteíne
- Recombinant
- Attributs du protein
- Isoform 3, AA 1-402
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette NR1H3 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MPHSAGGTAG VGLEAAEPTA LLTRAEPPSE PTEIRPQKRK KGPAPKMLGN ELCSVCGDKA SGFHYNVLSC EGCKGFFRRS VIKGAHYICH SGGHCPMDTY MRRKCQECRL RKCRQAGMRE ECVLSEEQIR LKKLKRQEEE QAHATSLPPR ASSPPQILPQ LSPEQLGMIE KLVAAQQQCN RRSFSDRLRV TPWPMAPDPH SREARQQRFA HFTELAIVSV QEIVDFAKQL PGFLQLSRED QIALLKTSAI EVMLLETSRR YNPGSESITF LKDFSYNRED FAKAGLQVEF INPIFEFSRA MNELQLNDAE FALLIAISIF SADRPNVQDQ LQVERLQHTY VEALHAYVSI HHPHDRLMFP RMLMKLVSLR TLSSVHSEQV FALRLQDKKL PPLLSEIWDV HE
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product NR1H3 Protéine
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Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-387) protein (GST tag)
NR1H3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-447) protein (Strep Tag)Crystallography grade NR1H3 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-445) protein (Strep Tag)Crystallography grade NR1H3 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NR1H3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Autre désignation
- NR1H3 (NR1H3 Produits)
- Synonymes
- NR1H3 Protein, LXR-a Protein, LXRA Protein, RLD-1 Protein, AU018371 Protein, LXR Protein, RLD1 Protein, Unr1 Protein, LXRalpha Protein, LXR-alpha Protein, im:7141239 Protein, wu:fd59b01 Protein, zgc:113339 Protein, zgc:158542 Protein, nuclear receptor subfamily 1 group H member 3 Protein, nuclear receptor subfamily 1, group H, member 3 Protein, NR1H3 Protein, nr1h3 Protein, Nr1h3 Protein
- Sujet
- Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elents characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism .
- Poids moléculaire
- 61.7 kDa
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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