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Frataxin Protein (FXN) (AA 81-210) (His tag)

FXN Origine: Cynomolgus Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711503
  • Antigène Voir toutes Frataxin (FXN) Protéines
    Frataxin (FXN)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 81-210
    Origine
    • 10
    • 4
    • 1
    • 1
    Cynomolgus
    Source
    • 9
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Frataxin protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    SGTLGHPGSL DDTTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDRTG KNWVYSHDGV SLHELLGAEL TKALKTKLDL SSLAYSGKDA
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product FXN Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    Frataxin (FXN)
    Autre désignation
    FRDA (FXN Produits)
    Synonymes
    zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
    Sujet
    Promotes the biosynthesis of he and assbly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 .
    Poids moléculaire
    18.3 kDa
    UniProt
    Q8HXX9
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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