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TMEM66 Protein (AA 195-339) (His-SUMO Tag)

TMEM66 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711690
  • Antigène Voir toutes TMEM66 Protéines
    TMEM66 (Transmembrane Protein 66 (TMEM66))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 195-339
    Origine
    • 3
    • 3
    • 1
    Humain
    Source
    • 6
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette TMEM66 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    SDGQYSPPPY SEYPPFSHRY QRFTNSAGPP PPGFKSEFTG PQNTGHGATS GFGSAFTGQQ GYENSGPGFW TGLGTGGILG YLFGSNRAAT PFSDSWYYPS YPPSYPGTWN RAYSPLHGGS GSYSVCSNSD TKTRTASGYG GTRRR
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product TMEM66 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    TMEM66 (Transmembrane Protein 66 (TMEM66))
    Autre désignation
    SARAF (TMEM66 Produits)
    Synonymes
    FOAP-7 Protein, SARAF Protein, XTP3 Protein, 1810045K07Rik Protein, tmem66 Protein, Tmem66 Protein, TMEM66 Protein, store-operated calcium entry associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor S homeolog Protein, transmembrane protein 66 Protein, SARAF Protein, Saraf Protein, saraf Protein, saraf.S Protein, MCYG_05410 Protein, MGYG_06464 Protein, Tsp_10089 Protein
    Sujet
    Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions.
    Poids moléculaire
    31.48 kDa
    UniProt
    Q96BY9
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