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EXO5 Protein (AA 1-373, full length) (His-SUMO Tag)

EXO5 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711779
  • Antigène Voir toutes EXO5 Protéines
    EXO5 (Exonuclease 5 (EXO5))
    Type de proteíne
    Recombinant
    Attributs du protein
    full length, AA 1-373
    Origine
    • 2
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette EXO5 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MAETREEETV SAEASGFSDL SDSEFLEFLD LEDAQESKAL VNMPGPSSES LGKDDKPISL QNWKRGLDIL SPMERFHLKY LYVTDLATQN WCELQTAYGK ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG ELELAELKTR RRPMLPLEAQ KKKDCFQVSL YKYIFDAMVQ GKVTPASLIH HTKLCLEKPL GPSVLRHAQQ GGFSVKSLGD LMELVFLSLT LSDLPVIDIL KIEYIHQETA TVLGTEIVAF KEKEVRAKVQ HYMAYWMGHR EPQGVDVEEA WKCRTCTYAD ICEWRKGSGV LSSTLAPQVK KAK
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product EXO5 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    EXO5 (Exonuclease 5 (EXO5))
    Autre désignation
    EXO5 (EXO5 Produits)
    Synonymes
    C1orf176 Protein, DEM1 Protein, Exo V Protein, hExo5 Protein, 3110037I16Rik Protein, AV297100 Protein, Dem1 Protein, mExo5 Protein, exonuclease 5 Protein, EXO5 Protein, Exo5 Protein
    Sujet
    Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting, however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'-directionality activity.
    Poids moléculaire
    57.8 kDa
    UniProt
    Q9H790
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