GNL3L Protein (AA 1-582, full length) (His-SUMO Tag)
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- Antigène Voir toutes GNL3L Protéines
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-582, full length
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GNL3L protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MMKLRHKNKK PGEGSKGHKK ISWPYPQPAK QNGKKATSKV PSAPHFVHPN DHANREAELK KKWVEEMREK QQAAREQERQ KRRTIESYCQ DVLRRQEEFE HKEEVLQELN MFPQLDDEAT RKAYYKEFRK VVEYSDVILE VLDARDPLGC RCFQMEEAVL RAQGNKKLVL VLNKIDLVPK EVVEKWLDYL RNELPTVAFK ASTQHQVKNL NRCSVPVDQA SESLLKSKAC FGAENLMRVL GNYCRLGEVR THIRVGVVGL PNVGKSSLIN SLKRSRACSV GAVPGITKFM QEVYLDKFIR LLDAPGIVPG PNSEVGTILR NCVHVQKLAD PVTPVETILQ RCNLEEISNY YGVSGFQTTE HFLTAVAHRL GKKKKGGLYS QEQAAKAVLA DWVSGKISFY IPPPATHTLP THLSAEIVKE MTEVFDIEDT EQANEDTMEC LATGESDELL GDTDPLEMEI KLLHSPMTKI ADAIENKTTV YKIGDLTGYC TNPNRHQMGW AKRNVDHRPK SNSMVDVCSV DRRSVLQRIM ETDPLQQGQA LASALKNKKK MQKRADKIAS KLSDSMMSAL DLSGNADDGV GD
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product GNL3L Protéine
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Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 1-582) protein (GST tag)
GNL3L Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 1-582) protein (Strep Tag)Crystallography grade GNL3L Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 1-577) protein (Strep Tag)Crystallography grade GNL3L Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 1-582), (full length) protein (His-SUMO Tag)GNL3L Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- Autre désignation
- GNL3L (GNL3L Produits)
- Synonymes
- SI:zK13A21.8 Protein, flj10613 Protein, flj10613l Protein, si:dkey-13a21.8 Protein, zgc:110536 Protein, BC020354 Protein, guanine nucleotide binding protein-like 3 (nucleolar)-like Protein, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog Protein, G protein nucleolar 3 like Protein, gnl3l Protein, gnl3l.S Protein, GNL3L Protein, Gnl3l Protein
- Sujet
- Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
- Poids moléculaire
- 81.53 kDa
- UniProt
- Q9NVN8
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