USH1C Protein (AA 1-533) (His-SUMO Tag)

N° du produit ABIN5712005

Détail du produit

Antigène: USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))

Type de proteíne: Recombinant

Attributs du protein: AA 1-533

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette USH1C protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEGRELFMT DRERLAEARQ RELQRQELLM QKRLAMESNK ILQEQQEMER QRRKEIAQKA AEENERYRKE MEQIVEEEEK FKKQWEEDWG SKEQLLLPKT ITAEVHPVPL RKPKYDQGVE PELEPADDLD GGTEEQGEQD FRKYEEGFDP YSMFTPEQIM GKDVRLLRIK KEGSLDLALE GGVDSPIGKV VVSAVYERGA AERHGGIVKG DEIMAINGKI VTDYTLAEAD AALQKAWNQG GDWIDLVVAV CPPKEYDDEL TFF

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))

Autre désignation: USH1C (USH1C Produits)

Synonymes: AIE-75 Protein, DFNB18 Protein, DFNB18A Protein, NY-CO-37 Protein, NY-CO-38 Protein, PDZ-45 Protein, PDZ-73 Protein, PDZ-73/NY-CO-38 Protein, PDZ73 Protein, PDZD7C Protein, ush1cpst Protein, 2010016F01Rik Protein, harmonin Protein, zgc:136806 Protein, ush1c Protein, USH1 protein network component harmonin Protein, harmonin Protein, Usher syndrome 1C Protein, USH1 protein network component harmonin L homeolog Protein, USH1C Protein, CpipJ_CPIJ012732 Protein, Ush1c Protein, ush1c Protein, ush1c.L Protein

Sujet: Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing .

Poids moléculaire: 76.3 kDa

UniProt: Q9Y6N9

Pathways: Sensory Perception of Sound