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IFITM1 Protein (AA 1-36, Extracellular) (GST tag)

IFITM1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712123
  • Antigène Voir toutes IFITM1 Protéines
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Type de proteíne
    Recombinant
    Attributs du protein
    Extracellular, AA 1-36
    Origine
    • 5
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette IFITM1 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MHKEEHEVAV LGAPPSTILP RSTVINIHSE TSVPDH
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product IFITM1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Autre désignation
    IFM1 (IFITM1 Produits)
    Synonymes
    9-27 Protein, CD225 Protein, DSPA2a Protein, IFI17 Protein, LEU13 Protein, 1110036C17Rik Protein, Mil-2 Protein, Mil2 Protein, interferon induced transmembrane protein 1 Protein, interferon induced transmembrane protein 1 (9-27) Protein, Ifitm1 Protein, IFITM1 Protein
    Sujet
    IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation
    Poids moléculaire
    31.3 kDa
    UniProt
    P13164
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