RRAGA Protein (AA 1-247, partial) (GST tag)

N° du produit ABIN5712295

Détail du produit

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-247, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RRAGA protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS)

Séquence: MPNTAMKKKV LLMGKSGSGK TSMRSIIFAN YIARDTRRLG ATIDVEHSHV RFLGNLVLNL WDCGGQDTFM ENYFTSQRDN IFRNVEVLIY VFDVESRELE KDMHYYQSCL EAILQNSPDA KIFCLVHKMD LVQEDQRDLI FKEREEDLRR LSRPLECACF RTSIWDETLY KAWSSIVYQL IPNVQQLEMN LRNFAQIIEA DEVLLFERAT FLVISHYQCK EQRDVHRFEK ISNIIKQFKL SCSKLAA

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Autre désignation: RRAGA (RRAGA Produits)

Synonymes: FIP-1 Protein, FIP1 Protein, RAGA Protein, 1300010C19Rik Protein, AI255374 Protein, Raga Protein, Ras related GTP binding A Protein, Ras-related GTP binding A Protein, RRAGA Protein, Rraga Protein

Sujet: Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Poids moléculaire: 56.4 kDa

UniProt: Q7L523