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PSME3 Protein (PSME3) (AA 2-252, partial) (GST tag)

PSME3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712868
  • Antigène Voir toutes PSME3 Protéines
    PSME3
    Type de proteíne
    Recombinant
    Attributs du protein
    partial, AA 2-252
    Origine
    • 7
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 6
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PSME3 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    ASLLKVDQEV KLKVDSFRER ITSEAEDLVA NFFPKKLLEL DSFLKEPILN IHDLTQIHSD MNLPVPDPIL LTNSHDGLDG PTYKKRRLDE CEEAFQGTKV FVMPNGMLKS NQQLVDIIEK VKPEIRLLIE KCNTVKMWVQ LLIPRIEDGN NFGVSIQEET VAELRTVESE AASYLDQISR YYITRAKLVS KIAKYPHVED YRRTVTEIDE KEYISLRLII SELRNQYVTL HDMILKNIEK IKRPRSSNAE T
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product PSME3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    PSME3
    Autre désignation
    PSME3 (PSME3 Produits)
    Synonymes
    AA410043 Protein, AU020960 Protein, Ki Protein, PA28gamma Protein, REGgamma Protein, pa28g Protein, Ab2-371 Protein, PA28-gamma Protein, PA28G Protein, REG-GAMMA Protein, psme3b Protein, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) Protein, proteasome activator subunit 3 Protein, proteasome activator subunit 3 S homeolog Protein, Psme3 Protein, PSME3 Protein, psme3.S Protein
    Sujet
    Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
    Poids moléculaire
    56.5 kDa
    UniProt
    P61289
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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